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Primary Intramedullary Spinal Cord Lymphoma Neurol 77:784-791, Flanagan, E.P.,et al, 2011 See this aricle in Pubmed Article Abstract PISCL mimics other causes of myelopathy. Spinal MRI demonstrating multifocal lesions, persistent gadolinium enhancement, and conus medullaris or cauda equine involvement is characteristic. Pathologic confirmation often requires CNS biopsy. Despite chemotherapy, morbidity and mortality is high.

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